The role of microbicidal lipids in host defense against pathogens and their potential as therapeutic agents.

@article{Thormar2007TheRO,
  title={The role of microbicidal lipids in host defense against pathogens and their potential as therapeutic agents.},
  author={Halld{\'o}r Thormar and Hilmar Þ{\'o}r Hilmarsson},
  journal={Chemistry and physics of lipids},
  year={2007},
  volume={150 1},
  pages={
          1-11
        }
}
Lipids such as fatty alcohols, free fatty acids and monoglycerides of fatty acids are known to be potent antimicrobial/microbicidal agents in vitro and to kill enveloped viruses, Gram-positive and Gram-negative bacteria and fungi on contact. For over half a century several studies have tried to answer the question of whether or not lipids play a role in the natural host defense against pathogens. A comprehensive review is given of these studies, particularly concerning infections in skin and in… CONTINUE READING
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