The role of microRNA-196a in tumorigenesis, tumor progression, and prognosis

@article{Chen2016TheRO,
  title={The role of microRNA-196a in tumorigenesis, tumor progression, and prognosis},
  author={Zhen-Yao Chen and Xin Mao Chen and Zhaoxia Wang},
  journal={Tumor Biology},
  year={2016},
  volume={37},
  pages={15457-15466}
}
MicroRNAs are a large group of non-coding RNAs that have emerged as regulators of various biological processes, especially carcinogenesis and cancer progression. Recent evidence has shown that microRNA-196a (miR-196a) is upregulated in most types of tumors and involved in multiple biological processes via translational inhibition and mRNA cleavage, such as cell proliferation, migration, and invasion, mostly functioning as an oncogene. Dysregulation of miR-196a promotes oncogenesis and tumor… CONTINUE READING