The role of methadone in the treatment of moderate to severe cancer pain.

@article{Shaiova2005TheRO,
  title={The role of methadone in the treatment of moderate to severe cancer pain.},
  author={Lauren A Shaiova},
  journal={Supportive cancer therapy},
  year={2005},
  volume={2 3},
  pages={176-80}
}
The World Health Organization recommends a step-by-step approach to the management of chronic cancer pain, called the analgesic ladder. Traditionally, morphine has been the prototypical opioid for chronic cancer pain because there is no ceiling effect or upper limit and it is a naturally occurring pure mu-opioid agonist. Occasionally, there are dose… CONTINUE READING