The role of mesolimbic dopaminergic and retrohippocampal afferents to the nucleus accumbens in latent inhibition: implications for schizophrenia.

@article{Gray1995TheRO,
  title={The role of mesolimbic dopaminergic and retrohippocampal afferents to the nucleus accumbens in latent inhibition: implications for schizophrenia.},
  author={Jeffrey A. Gray and Michael H. Joseph and David R. Hemsley and Adrienne M Young and E. Clea Warburton and P. Boulenguez and G. A. Grigoryan and Scott Peters and J. Nicholas P. Rawlins and C T Taib},
  journal={Behavioural brain research},
  year={1995},
  volume={71 1-2},
  pages={19-31}
}
Latent inhibition (LI) consists in a retardation of conditioning seen when the to-be-conditioned stimulus is first presented a number of times without other consequence. Disruption of LI has been proposed as a possible model of the cognitive abnormality that underlies the positive psychotic symptoms of acute schizophrenia. We review here evidence in support of the model, including experiments tending to show that: (1) disruption of LI is characteristic of acute, positively-symptomatic… CONTINUE READING
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J.N.P., Both electrolytic and excitotoxic lesions of nucleus accumbens disrupt latent inhibition in rats, Neurobiol

  • Tai, C.-T, H. J. Cassaday, J. Feldon, Rawlins
  • Learning Memory,
  • 1995

Cognitive disturbance as the link between schizophrenic symptoms and their biological bases

  • D. R. Hemsley
  • Neurol . Psychiatry Brain Res .
  • 1994

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