The role of mesenchymal stem cells in the functional improvement of chronic renal failure.

  title={The role of mesenchymal stem cells in the functional improvement of chronic renal failure.},
  author={Soojeong Choi and Mooyong Park and Jinkuk Kim and Seungduk Hwang and Seongkyu Park and Youkyoung Lee},
  journal={Stem cells and development},
  volume={18 3},
The most commonly used therapeutic targets in nephrology are the reduction of injury, the delay of progression, or renal replacement therapy. Many animal and human studies demonstrated the role of stem cells in repair and regenerations of kidney. Mesenchymal stem cells (MSCs) have shown to improve outcome of acute renal injury models. It is controversial whether MSCs can reduce injury following a toxic/ischemic event and delay renal failure in chronic kidney disease. We evaluated the hypothesis… CONTINUE READING


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