The role of melatonin in the pathogenesis of hypertension in rats with metabolic syndrome.

@article{Leibowitz2008TheRO,
  title={The role of melatonin in the pathogenesis of hypertension in rats with metabolic syndrome.},
  author={Avshalom Leibowitz and Edna Peleg and Yhenoatan Sharabi and Zehava Shabtai and Ari Shamiss and Ehud Grossman},
  journal={American journal of hypertension},
  year={2008},
  volume={21 3},
  pages={348-51}
}
BACKGROUND Melatonin, the primary hormone of the pineal gland, is a known modulator of various physiological processes. The aim of this study was to evaluate the role of melatonin in the pathogenesis of hypertension in rats with metabolic syndrome and to assess whether melatonin supplementation prevents the development of hypertension in this model. METHODS Twenty male Sprague-Dawley (SD) rats were fed either a high fructose diet (n = 10) or a regular diet (control; n = 10) for 5 weeks… CONTINUE READING

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