The role of mechanics during brain development.

  title={The role of mechanics during brain development.},
  author={Silvia Budday and Paul Steinmann and Ellen Kuhl},
  journal={Journal of the mechanics and physics of solids},
Convolutions are a classical hallmark of most mammalian brains. Brain surface morphology is often associated with intelligence and closely correlated to neurological dysfunction. Yet, we know surprisingly little about the underlying mechanisms of cortical folding. Here we identify the role of the key anatomic players during the folding process: cortical thickness, stiffness, and growth. To establish estimates for the critical time, pressure, and the wavelength at the onset of folding, we derive… CONTINUE READING
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