The role of mast cells in the development of 2, 4, 6-trinitrobenzene sulfonic acid-induced colitis in rats.

Abstract

BACKGROUND The role of mast cells in Crohn disease (CD) remains to be established. The aim of this study was to elucidate this in the development of CD-like colitis in rats by the use of mast-cell-deficient Ws/Ws and their control W+/W+ rats. METHODS CD-like colitis was induced in both groups by an enema of 10 mg of 2,4, 6-trinitrobenzene sulfonic acid… (More)

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@article{Fukumoto2002TheRO, title={The role of mast cells in the development of 2, 4, 6-trinitrobenzene sulfonic acid-induced colitis in rats.}, author={Yukio Fukumoto and Hiroshi Kasai and H. Takahashi and H. Sugiyama and N. Hase and Hitomi Kaneko and Ichiro Hamamura and Y. Aoki and Martin O C Ota and Takashi Kobayashi and Yasuhiro Katsuura and T. Kamimura and Kenji Komoriya}, journal={Scandinavian journal of gastroenterology}, year={2002}, volume={37 5}, pages={555-60} }