• Corpus ID: 33716552

The role of magnesium binders in chronic kidney disease.

  title={The role of magnesium binders in chronic kidney disease.},
  author={David M. Spiegel},
  journal={Seminars in dialysis},
  volume={20 4},
  • D. Spiegel
  • Published 2007
  • Medicine
  • Seminars in dialysis
Magnesium is predominantly an intracellular cation that plays a critical role in cellular physiology. Serum levels are often slightly elevated in patients on chronic hemodialysis and older reports suggests that total body stores may also be increased, based on bone biopsies in patients treated with higher dialysate magnesium levels than are currently in use today. Several studies have shown that magnesium, particularly in the form of magnesium carbonate, is an effective phosphate binder and can… 
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  • 2011
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There was a significant negative correlation between serum levels of PTH and zinc as well as an insignificantnegative correlation between P TH and serum magnesium in CRF patients, indicating that Elevated PTH may play a role in the pathogenesis of hypozincemia.
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