The role of macrophages in skeletal muscle regeneration with particular reference to chemotaxis.

@article{Robertson1993TheRO,
  title={The role of macrophages in skeletal muscle regeneration with particular reference to chemotaxis.},
  author={Terry A Robertson and Moira Alison Maley and Miranda D Grounds and John M. Papadimitriou},
  journal={Experimental cell research},
  year={1993},
  volume={207 2},
  pages={321-31}
}
The results from this investigation suggest that chemotactic factor(s) from damaged myofibers attract polymorphonuclear leukocytes (PML) and macrophages to the site of injury, while exudate macrophages but not PML induce a strong positive chemotactic response in myogenic cells. The AB and BB isoforms of platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-beta), basic fibroblast growth factor (bFGF), and leukemia inhibitory factor (LIF) (all of these are secreted by… CONTINUE READING

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