The role of local protein synthesis and degradation in axon regeneration

@inproceedings{Gumy2010TheRO,
  title={The role of local protein synthesis and degradation in axon regeneration},
  author={Laura F. Gumy and Chin Lik Tan and James W. Fawcett},
  booktitle={Experimental Neurology},
  year={2010}
}
In axotomised regenerating axons, the first step toward successful regeneration is the formation of a growth cone. This requires a variety of dynamic morphological and biochemical changes in the axon, including the appearance of many new cytoskeletal, cell surface and signalling molecules. These changes suggest the activation of coordinated complex cellular processes. A recent development has been the demonstration that the regenerative ability of some axons depends on their capacity to locally… CONTINUE READING

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