The role of lipoprotein receptors on the physiological function of APP

@article{Wagner2011TheRO,
  title={The role of lipoprotein receptors on the physiological function of APP},
  author={Timo Wagner and Claus U. Pietrzik},
  journal={Experimental Brain Research},
  year={2011},
  volume={217},
  pages={377-387}
}
In this review, we will primarily focus on the role of members of the low-density lipoprotein receptor (LDL-R) family that are involved in trafficking and processing of the amyloid precursor protein (APP). We will discuss the role of the LDL-receptor family members, low-density lipoprotein receptor-related protein 1 (LRP1), LRP1b, apolipoprotein E receptor 2, sortilin-related receptor (SorLA/LR11) and megalin/LRP2 on the physiological function of APP and its cellular localization. Additionally… CONTINUE READING

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