• DOI:10.1126/SCIENCE.111.2877.166
• Corpus ID: 8265504

The role of lipids and lipoproteins in atherosclerosis.

@article{Gofman1950TheRO,
  title={The role of lipids and lipoproteins in atherosclerosis.},
  author={John W. Gofman and Frank T. Lindgren},
  journal={Science},
  year={1950},
  volume={111 2877},
  pages={
          166-71
        }
}

• J. Gofman, F. Lindgren
• Published 17 February 1950
• Medicine
• Science

A THEROSCLEROSIS is generally considered to be the major disease of this era. Its consequences in the coronary, cerebral, and peripheral arteries, in the form o£ ocelu- sive phenomena, are responsible for more death and disability than any other disease. In spite of much study and research there is still no agreement con- cerning the sequence of pathogenetic events, etiol- ogy, or treatment of atheroselerosis. The not-too- rare oceurrence of coronary artery ocelusions (almost always a consequence of atheroselerosis) in young men from 20 to 40 years of age testifies to the fallacy of the idea, still prevalent, that atheroselerosis is a problem of the aged or senile. For the male it is a