[The role of lipid metabolism disorders in the mechanism of the hepatotoxic effects of rubomycin].

Abstract

The phase character of the changes in the contents of lipids and phospholipids and impairment of the ratio of separate fractions in the liver mitochondria after discontinuation of rubomycin (daunorubicin) administration were studied in the time course of 35 days. The impairments were accompanied by activation of lipid peroxidation. By the end of the experiment (on the 35th day) there was noted a tendency to normalization of the indices studied.

Cite this paper

@article{Saprykina1988TheRO, title={[The role of lipid metabolism disorders in the mechanism of the hepatotoxic effects of rubomycin].}, author={E. V. Saprykina and B Iu Sal'nik}, journal={Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]}, year={1988}, volume={33 6}, pages={452-5} }