The role of leptin in osteoarthritis

BACKGROUND The pathogenesis of osteoarthritis (OA) is not clear; leptin may be related to its pathogenesis. METHODS We reviewed articles on leptin in OA, chondrocytes, and in vitro experiments. It is concluded that leptin may lead to OA via some signaling pathways. At the same time, the concentration of leptin in vitro experiments and OA/rheumatoid… CONTINUE READING