• Medicine
  • Published in Acta chirurgica Belgica 1996

The role of lactulose in the prevention of bacterial translocation in surgical trauma.

@article{Ozelik1996TheRO,
  title={The role of lactulose in the prevention of bacterial translocation in surgical trauma.},
  author={M F Ozçelik and Cafer Eroğlu and Salih Pekmezci and Recep Ozt{\"u}rk and Melih Paksoy and Mesut Negizade and Mehmet Ali Vardar},
  journal={Acta chirurgica Belgica},
  year={1996},
  volume={96 1},
  pages={
          44-8
        }
}
Surgical trauma (ST) is one of the causative factor of bacterial translocation. In this study we investigated the prevention of bacterial translocation with lactulose in a surgical trauma model. The study was designed in 3 experimental groups consisting of 15 rats in each. Group 1 was sham operated controls, group 2 was ST + physiologic saline treated and group 3 was ST + lactulose treated animals. Lactulose and physiologic saline were given by oro-gastric intubation in a dose of 2 ml of 33.5… CONTINUE READING