Corpus ID: 41695709

The role of iodine in autoimmune thyroiditis.

  title={The role of iodine in autoimmune thyroiditis.},
  author={N. Rose and A. M. Saboori and L. Rasooly and C. L. Burek},
  journal={Critical reviews in immunology},
  volume={17 5-6},
  • N. Rose, A. M. Saboori, +1 author C. L. Burek
  • Published 1997
  • Medicine
  • Critical reviews in immunology
  • Like most cancers, autoimmune diseases generally are due to the interaction of a number of genetic traits with an environmental trigger. Autoimmune thyroiditis, a model of organ-specific autoimmune disease, is associated with iodine as a precipitating environmental factor. T cells from patients with chronic thyroiditis proliferate in response to normal human thyroglobulin, but fail to react with non-iodinated thyroglobulin. Using a selected monoclonal antibody, we were able to identify a… CONTINUE READING
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