The role of introns in repeat protein gene formation.

@article{Street2006TheRO,
  title={The role of introns in repeat protein gene formation.},
  author={Timothy O Street and George D. Rose and Doug Barrick},
  journal={Journal of molecular biology},
  year={2006},
  volume={360 2},
  pages={258-66}
}
Genes composed of tandem repetitive sequence motifs are abundant in nature and are enriched in eukaryotes. To investigate repeat protein gene formation mechanisms, we have conducted a large-scale analysis of their introns and exons. We find that a wide variety of repeat motifs exhibit a striking conservation of intron position and phase, and are composed of exons that encode one or two complete repeats. These results suggest a simple model of repeat protein gene formation from local… CONTINUE READING
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