The role of interleukin-1beta in febrile seizures.

@article{Heida2009TheRO,
  title={The role of interleukin-1beta in febrile seizures.},
  author={James G Heida and Solomon L Mosh{\'e} and Quentin J Pittman},
  journal={Brain & development},
  year={2009},
  volume={31 5},
  pages={388-93}
}
Febrile seizures (FS) occur in children as a result of fever. Despite their prevalence, the pathophysiology of FS has remained unclear. Recent evidence from clinical and experimental studies has highlighted a potential role of immune generated products in the genesis of FS. Of particular interest are the pro-inflammatory cytokine, interleukin-1beta (IL-1beta) and its naturally occurring antagonist, interleukin 1 receptor antagonist (IL-1ra). Using a novel animal model of FS, involving the… CONTINUE READING

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