The role of interferons in early pregnancy

  title={The role of interferons in early pregnancy},
  author={Annalise Micallef and Nicole Grech and Francesca Farrugia and Pierre Schembri-Wismayer and Jean Calleja-Agius},
  journal={Gynecological Endocrinology},
  pages={1 - 6}
Abstract The interferons (IFNs) form part of the large family of glycoproteins known as cytokines. They are secreted by host cells as a line of defence against pathogens and certain tumours. IFNs affect cell proliferation and differentiation and also play a very important role in the functioning of the immune system. Miscarriage in both humans has been associated with higher levels of IFN, particularly IFN-γ. However, this cytokine is evidently vital in successful murine pregnancies since it is… 

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