The role of integrins in granulocyte dysfunction in myelodysplastic syndrome.

Abstract

The aim of the present study was to evaluate the function of granulocytes in 20 patients affected by myelodysplastic syndrome (MDS) and correlate this with the expression of surface membrane integrins. The granulocytes showed a deficit in chemotaxis (34 +/- 12 vs 84 +/- 10, p < 0.01) in superoxide release (12 +/- 7 vs 30 +/- 10, p < 0.01) and in aggregation… (More)

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Cite this paper

@article{Ricevuti1993TheRO, title={The role of integrins in granulocyte dysfunction in myelodysplastic syndrome.}, author={G. Ricevuti and Amelia Mazzone and Davide Pasotti and G. Fossati and Iolanda Mazzucchelli and Ana Fl{\'a}via Oliveira Not{\'a}rio}, journal={Leukemia research}, year={1993}, volume={17 7}, pages={609-19} }