The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications for treatment.

@article{Watson2003TheRO,
  title={The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications for treatment.},
  author={Ginger S. Watson and Suzanne Craft},
  journal={CNS drugs},
  year={2003},
  volume={17 1},
  pages={
          27-45
        }
}
An emerging body of evidence suggests that an increased prevalence of insulin abnormalities and insulin resistance in Alzheimer's disease may contribute to the disease pathophysiology and clinical symptoms. It has long been known that insulin is essential for energy metabolism in the periphery. In the past 2 decades, convergent findings have begun to demonstrate that insulin also plays a role in energy metabolism and other aspects of CNS function. Investigators reported 20 years ago that… CONTINUE READING
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