The role of insulin in the modulation of glucagon-dependent control of phenylalanine hydroxylation in isolated liver cells.

Abstract

The stimulation of phenylalanine hydroxylation in isolated liver cells by sub-maximally effective concentrations of glucagon (less than 0.1 microM) is antagonized by insulin (0.1 nM-0.1 microM). This phenomenon is a consequence of a decrease in the glucagon-stimulated phosphorylation of phenylalanine hydroxylase from liver cells incubated in the presence of… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.