The role of innate immunity activation in house dust mite allergy.

@article{Jacquet2011TheRO,
  title={The role of innate immunity activation in house dust mite allergy.},
  author={Alain Jacquet},
  journal={Trends in molecular medicine},
  year={2011},
  volume={17 10},
  pages={
          604-11
        }
}
House dust mite (HDM) allergy is a frequent inflammatory disease found worldwide. Although allergen-specific CD4(+) Th2 cells orchestrate the HDM allergic response, notably through induction of IgE directed towards mite allergens, recent studies have demonstrated that innate immunity activation also plays a critical role in HDM-induced allergy pathogenesis. HDM allergens can not only be considered proteins that induce adaptive Th2-biased responses in susceptible subjects but also as strong… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 70 REFERENCES

Genetic variations in toll-like receptor pathway genes influence asthma and atopy

R Tesse
  • Allergy
  • 2011

A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis

de Koning, H.D
  • J. Invest. Dermatol
  • 2010

EGFR signaling contributes to house dust miteinduced epithelial barrier dysfunction

Heijink, I.H
  • Eur. Respir. J
  • 2010

Functional interaction of common allergens and a C-type lectin receptor, DC-specific ICAM3-grabbing non-integrin (DC-sign), on human DCs

Hsu, S.C
  • J. Biol
  • 2010

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