The role of inflammatory cytokines as key modulators of neurogenesis

  title={The role of inflammatory cytokines as key modulators of neurogenesis},
  author={Alessandra Borsini and Patricia Ana Zunszain and Sandrine Thuret and Carmine M Pariante},
  journal={Trends in Neurosciences},
Neurogenesis is an important process in the regulation of brain function and behaviour, highly active in early development and continuing throughout life. Recent studies have shown that neurogenesis is modulated by inflammatory cytokines in response to an activated immune system. To disentangle the effects of the different cytokines on neurogenesis, here we summarise and discuss in vitro studies on individual cytokines. We show that inflammatory cytokines have both a positive and negative role… CONTINUE READING
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