The role of inflammation in the pathology of acne.

  title={The role of inflammation in the pathology of acne.},
  author={Emil A. Tanghetti},
  journal={The Journal of clinical and aesthetic dermatology},
  volume={6 9},
The conventional perspective of acne pathogenesis holds that Propionibacterium acnes colonizes the duct of the sebaceous follicle, causing an innate immune response and the progression from a so-called noninflammatory comedo to an inflammatory papule, pustule, or nodule. However, this viewpoint has come under increasing scrutiny over the last decade, as evidence has emerged supporting a role for inflammation at all stages of acne lesion development, perhaps subclinically even before comedo… CONTINUE READING
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