The role of inflammation in ICU-acquired weakness

  title={The role of inflammation in ICU-acquired weakness},
  author={Chris Winkelman},
  booktitle={Critical care},
A pilot observational study by Weber-Carstens and colleagues contributes to a mechanistic explanation of the puzzling and complex phenomena of ICU-acquired weakness (ICU-AW). The authors suggest systemic, inflammatory-mediated pathology is the most significant risk factor for ICU-AW. While this finding is somewhat equivocal, it provides important direction for future investigations and illustrates the challenges of interpreting significance in small observational studies. 
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Beyond the clinical phenotype : the biologic integratome

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