The role of inflammation and macrophage accumulation in the development of obesity-induced type 2 diabetes mellitus and the possible therapeutic effects of long-chain n-3 PUFA

@article{Oliver2010TheRO,
  title={The role of inflammation and macrophage accumulation in the development of obesity-induced type 2 diabetes mellitus and the possible therapeutic effects of long-chain n-3 PUFA},
  author={E. Oliver and Fiona C. McGillicuddy and Catherine M Phillips and Sinead Toomey and Helen M. Roche},
  journal={Proceedings of the Nutrition Society},
  year={2010},
  volume={69},
  pages={232 - 243}
}
The WHO estimate that >1×106 deaths in Europe annually can be attributed to diseases related to excess body weight, and with the rising global obesity levels this death rate is set to drastically increase. Obesity plays a central role in the metabolic syndrome, a state of insulin resistance that predisposes patients to the development of CVD and type 2 diabetes mellitus. Obesity is associated with low-grade chronic inflammation characterised by inflamed adipose tissue with increased macrophage… Expand
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