The role of immune complexes in the pathogenesis of disease.

  title={The role of immune complexes in the pathogenesis of disease.},
  author={Brian S. Andrews and Ronald Penny},
  journal={Australian and New Zealand journal of medicine},
  volume={6 6},
Circulating antigen-antibody complexes are incriminated in the pathogenesis of auto-immune and inflammatory disease, and more recently malignancy. Extensive knowledge of the immunopathological reactions has evolved from from the study of experimental serum sickness in animals and of the potential aetiological agents (e.g. viruses) from spontaneous immune complex diseases in animals. Numerous techniques, both direct and indirect, have now been described to identify immune complexes in serum… CONTINUE READING
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