The role of immune cells in metabolism-related liver inflammation and development of non-alcoholic steatohepatitis (NASH)

@article{Nati2016TheRO,
  title={The role of immune cells in metabolism-related liver inflammation and development of non-alcoholic steatohepatitis (NASH)},
  author={Marina Nati and David Haddad and Andreas L Birkenfeld and Christian A. Koch and Triantafyllos Chavakis and Antonios Chatzigeorgiou},
  journal={Reviews in Endocrine and Metabolic Disorders},
  year={2016},
  volume={17},
  pages={29-39}
}
The low grade inflammatory state present in obesity promotes the progression of Non-Alcoholic Fatty Liver Disease (NAFLD). In Non-Alcoholic Steatohepatitis (NASH), augmented hepatic steatosis is accompanied by aberrant intrahepatic inflammation and exacerbated hepatocellular injury. NASH is an important disorder and can lead to fibrosis, cirrhosis and even neoplasia. The pathology of NASH involves a complex network of mechanisms, including increased infiltration of different subsets of immune… CONTINUE READING
14 Citations
164 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 164 references

Similar Papers

Loading similar papers…