The role of hypoxia inducible factor in nasal inflammations.

@article{Cheng2016TheRO,
  title={The role of hypoxia inducible factor in nasal inflammations.},
  author={K J Cheng and Y-Y Bao and Shibin Zhou},
  journal={European review for medical and pharmacological sciences},
  year={2016},
  volume={20 24},
  pages={5067-5076}
}
OBJECTIVE Hypoxia-inducible factor (HIF) is considered an important transcription factor due to its roles in glycolysis, angiogenesis, cell differentiation, apoptosis, and other cellular pathways. It takes the role in various physiological and pathological states, such as solid tumors, vascular injury, and atherosclerotic lesion progression. In recent studies, HIF is found as a master regulator of body inflammation and immunity, not only in hypoxia but also in normoxia. Nasal inflammation has a… CONTINUE READING

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