The role of hypoxia inducible factor in nasal inflammations.

  title={The role of hypoxia inducible factor in nasal inflammations.},
  author={K J Cheng and Y-Y Bao and Shibin Zhou},
  journal={European review for medical and pharmacological sciences},
  volume={20 24},
OBJECTIVE Hypoxia-inducible factor (HIF) is considered an important transcription factor due to its roles in glycolysis, angiogenesis, cell differentiation, apoptosis, and other cellular pathways. It takes the role in various physiological and pathological states, such as solid tumors, vascular injury, and atherosclerotic lesion progression. In recent studies, HIF is found as a master regulator of body inflammation and immunity, not only in hypoxia but also in normoxia. Nasal inflammation has a… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 149 references

FM 19 G 11 reverses endothelial dysfunction in rat and human arteries through stimulation of the PI 3 K / Akt / eNOS pathway , independently of mTOR / HIF - 1 α activation

M elaSSar, JM Sánchez-PuelleS, +4 authors J anGulo

GoSker hr, VerheeS kJ, lanGen rc, ScholS aM. TNF-α-induced NF-κB activation stimulates skeletal muscle glycolytic metabolism through activation of HIF-1α

reMelS ah
Endocrinology • 2015

Similar Papers

Loading similar papers…