The role of hyperhomocysteinemia as well as folate, vitamin B6 and B12 deficiencies in osteoporosis – a systematic review

@inproceedings{Herrmann2007TheRO,
  title={The role of hyperhomocysteinemia as well as folate, vitamin B6 and B12 deficiencies in osteoporosis – a systematic review},
  author={Markus Herrmann and Johannes Peter Schmidt and Natalia Umanskaya and Alexandra Wagner and Omid Taban-Shomal and Thomas Widmann and Graziana Colaianni and Britt Wildemann and Wolfgang Herrmann},
  booktitle={Clinical chemistry and laboratory medicine},
  year={2007}
}
Abstract Hyperhomocysteinemia (HHCY) has been suggested as a new risk factor for osteoporosis. Recent epidemiological, clinical and experimental studies provide a growing body of data, which is reviewed in this article. Epidemiological and (randomized) clinical trials suggest that HHCY increases fracture risk, but has minor effects on bone mineral density. Measurement of biochemical bone turnover markers indicates a shift of bone metabolism towards bone resorption. Animal studies confirm these… 

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TLDR
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Hyperhomocysteinemia disturbs fracture healing in mice
  • Medicine, Biology
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TLDR
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Low serum folate and vitamin B-6 are associated with an altered cancellous bone structure in humans.
TLDR
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