The role of human papillomavirus infection in head and neck cancers.

@article{Syrjnen2010TheRO,
  title={The role of human papillomavirus infection in head and neck cancers.},
  author={Stina M Syrj{\"a}nen},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2010},
  volume={21 Suppl 7},
  pages={vii243-5}
}
The link between head and neck squamous cell cancer (HNSCC), especially oropharyngeal cancer, and HPV has become established. HPV16 is the most common genotype in these tumours but HPV6 and HPV11 can also be found in a minority of these cancers, implying that these low-risk HPV types are not entirely benign in the head and neck region. HPV status is also associated with p16 expression and HPV+ tumours are less likely to harbour p53 mutations. HPV DNA is closely associated with poorly… CONTINUE READING
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The role of human papillomavirus in head and neck cancer

  • CB Lajer, C. von Buchwald
  • APMIS
  • 2010
Highly Influential
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