The role of hormones and aromatase inhibitors on breast tumor growth and general health in a postmenopausal mouse model

@article{Arumugam2014TheRO,
  title={The role of hormones and aromatase inhibitors on breast tumor growth and general health in a postmenopausal mouse model},
  author={A. Arumugam and Elaine A Lissner and R. Lakshmanaswamy},
  journal={Reproductive Biology and Endocrinology : RB&E},
  year={2014},
  volume={12},
  pages={66 - 66}
}
  • A. Arumugam, Elaine A Lissner, R. Lakshmanaswamy
  • Published 2014
  • Medicine
  • Reproductive Biology and Endocrinology : RB&E
  • BackgroundBreast cancer is the most frequently diagnosed cancer in women in the United States. [...] Key MethodMethodsOvariectomized nude mice were transplanted with MCF-7 breast cancer cells constitutively expressing aromatase. The mice were treated with different combinations and doses of steroids, [estrogen (25 pg, 40 pg, 100 pg), progesterone (6 ng) and testosterone (50 ng)] along with dehydroepiandrostenedione (100 ug).Expand Abstract
    Decisive tools of breast cancer: Advances in technologies

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 103 REFERENCES
    Prevention of breast cancer: current state of the science and future opportunities
    21
    The intratumoral aromatase model: studies with aromatase inhibitors and antiestrogens
    28
    Toxicity of aromatase inhibitors.
    12
    Changing concepts: Menopausal hormone therapy and breast cancer.
    120