The role of homocysteine in multisystem age-related problems: a systematic review.

@article{Kuo2005TheRO,
  title={The role of homocysteine in multisystem age-related problems: a systematic review.},
  author={Hsu-Ko Kuo and Farzaneh A. Sorond and J Chen and Ardeshir Z Hashmi and William P. Milberg and Lewis A. Lipsitz},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  year={2005},
  volume={60 9},
  pages={1190-201}
}
Homocysteine is a sulfur-containing amino acid that is involved in one-carbon metabolism. Hyperhomocysteinemia is a common phenomenon among elderly people. There is growing evidence of an association between hyperhomocysteinemia and geriatric multisystem problems, including coronary artery disease, stroke, peripheral vascular disease, cognitive impairment, dementia, depression, osteoporotic fractures, and functional decline. The proposed mechanisms of the association include angiotoxicity… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Vitamin B12 and homocysteine levels and 6-year change in peripheral nerve function and neurological signs.

The journals of gerontology. Series A, Biological sciences and medical sciences • 2012

References

Publications referenced by this paper.
Showing 1-10 of 138 references

Vitamin B12, folate, and homocysteine in depression: the Rotterdam Study.

The American journal of psychiatry • 2002
View 9 Excerpts
Highly Influenced

Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort.

The American journal of clinical nutrition • 2001
View 4 Excerpts
Highly Influenced

Homocysteine levels and the risk of osteoporotic fracture.

The New England journal of medicine • 2004
View 3 Excerpts
Highly Influenced

[Plasma homocysteine predicts mortality independently of traditional risk factors and C-reactive protein in patients with angiographically defined coronary artery disease].

Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology • 2001
View 10 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…