The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle.

@article{StookeVaughan2012TheRO,
  title={The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle.},
  author={Georgina A. Stooke-Vaughan and Peng Huang and Katherine L. Hammond and Alexander F Schier and Tanya T. Whitfield},
  journal={Development},
  year={2012},
  volume={139 10},
  pages={1777-87}
}
Otoliths are biomineralised structures required for the sensation of gravity, linear acceleration and sound in the zebrafish ear. Otolith precursor particles, initially distributed throughout the otic vesicle lumen, become tethered to the tips of hair cell kinocilia (tether cilia) at the otic vesicle poles, forming two otoliths. We have used high-speed video microscopy to investigate the role of cilia and ciliary motility in otolith formation. In wild-type ears, groups of motile cilia are… CONTINUE READING