The role of gonadal hormones in neuromuscular synapse elimination in rats. II. Multiple innervation persists in the adult levator ani muscle after juvenile androgen treatment.

@article{Jordan1989TheRO,
  title={The role of gonadal hormones in neuromuscular synapse elimination in rats. II. Multiple innervation persists in the adult levator ani muscle after juvenile androgen treatment.},
  author={Cynthia Lee Jordan and M S Letinsky and Arthur P. Arnold},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1989},
  volume={9 1},
  pages={239-47}
}
In the previous study (Jordan et al., 1989), we demonstrated that androgen treatment of juvenile male rats inhibits the elimination of synapses in the levator ani (LA) muscle. In the present study, we asked whether synapse elimination would occur once this juvenile androgen treatment ended. Castrated male rats were given androgen during a juvenile treatment period (7-34 d) and were killed 4 or 8 weeks after the end of androgen treatment (at 9 or 13 weeks after birth). The adult pattern of… CONTINUE READING