The role of glycans in the development and progression of prostate cancer

@article{Munkley2016TheRO,
  title={The role of glycans in the development and progression of prostate cancer},
  author={Jennifer Munkley and Ian G. Mills and David J. Elliott},
  journal={Nature Reviews Urology},
  year={2016},
  volume={13},
  pages={324-333}
}
Prostate cancer is a unique and heterogeneous disease. Currently, a major unmet clinical need exists to develop biomarkers that enable indolent disease to be distinguished from aggressive disease. The prostate is an abundant secretor of glycoproteins of all types, and alterations in glycans are, therefore, attractive as potential biomarkers and therapeutic targets. Despite progress over the past decade in profiling the genome and proteome, the prostate cancer glycoproteome remains relatively… Expand
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