The role of glutathione in cadmium ion detoxification: coordination modes and binding properties--a density functional study.
@article{Belcastro2009TheRO,
title={The role of glutathione in cadmium ion detoxification: coordination modes and binding properties--a density functional study.},
author={Marcella Belcastro and Tiziana Marino and Nino Russo and Marirosa Toscano},
journal={Journal of inorganic biochemistry},
year={2009},
volume={103 1},
pages={
50-7
}
}
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References
SHOWING 1-10 OF 103 REFERENCES
CADMIUM-BINDING PROPERTIES OF GLUTATHIONE: A CHEMOMETRICAL ANALYSIS OF VOLTAMMETRIC DATA
- Chemistry
- 1997
Interaction of cysteine with Cu2+ and group IIb (Zn2+, Cd2+, Hg2+) metal cations: a theoretical study.
- ChemistryJournal of mass spectrometry : JMS
- 2005
The structure and energetics of complexes obtained upon interaction between cysteine and Zn2+, Cd2+, Hg2+ and Cu2+ cations were studied using quantum chemical density functional theory calculations…
Structure and coordination modes in the interaction between Cd2+ and 3-mercaptopropionic acid
- Chemistry
- 2004
The structural, electronic, and energetic properties of cadmium ion complexes with one and two protonated and deprotonated 3-mercaptopropionic acid ligands were studied theoretically in the framework…
Spectral studies on copper(II) complexes of biologically active glutathione.
- ChemistrySpectrochimica acta. Part A, Molecular and biomolecular spectroscopy
- 2003
Interaction of Cu+ and Cu2+ ions with α-alanine. A density functional study
- Chemistry
- 2002
The Cu(+) and Cu(2+) preferred binding sites on alpha-alanine and their affinity values for this amino acid were determined at the density functional level using three different hybrid exchange…
Ligand-induced changes in the structure and dynamics of a human class Mu glutathione S-transferase.
- Biology, ChemistryBiochemistry
- 2000
The dynamic properties of GSTM2-2 were investigated over a wide range of time scales using (15)N nuclear spin relaxation, residual dipolar couplings, and amide hydrogen-deuterium exchange rates, showing that the majority of the protein backbone is rigid on the nanosecond to picosecond time scale for all forms of the enzyme.
Ca, Cd, Zn, and their ions interacting with Cytosine: a theoretical study.
- ChemistryThe journal of physical chemistry. A
- 2007
Analyses of the energetics of the global reactions to form cationic species show that metal cations bind more strongly to neutral cytosine than to neutral metals.
Cobalt(II) complexes of biologically active glutathione: spectroscopic and molecular modeling studies.
- ChemistrySpectrochimica acta. Part A, Molecular and biomolecular spectroscopy
- 2006
1H,13C-NMR and X-ray absorption studies of copper(I) glutathione complexes.
- ChemistryEuropean journal of biochemistry
- 1996
The high thermodynamic stability of Cu(I)-S bonds in Cu (I)-glutathione complexes coupled with their kinetic lability may provide efficient and specific pathways for the transport of copper in cells.