• DOI:10.1016/j.jinorgbio.2008.09.002
Corpus ID: 5320191

The role of glutathione in cadmium ion detoxification: coordination modes and binding properties--a density functional study.

@article{Belcastro2009TheRO,
  title={The role of glutathione in cadmium ion detoxification: coordination modes and binding properties--a density functional study.},
  author={M. Belcastro and T. Marino and N. Russo and M. Toscano},
  journal={Journal of inorganic biochemistry},
  year={2009},
  volume={103 1},
  pages={
          50-7
        }
}

M. Belcastro, T. Marino, +1 author M. Toscano

Published 2009

Chemistry, Medicine

Journal of inorganic biochemistry

In this investigation the reduced form of glutathione molecule (GSH) was considered as a model in the coordination chemistry of Cd(2+) and group thiol-containing peptides. Three different forms of GSH, corresponding to the prevalent ones in gas-phase and in aqueous solution, were taken into account in the metallation process. The obtained complexes were characterized at the density functional B3LYP level with the purpose to give better insight in the chelation mechanism of GSH with heavy metal… CONTINUE READING

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