The role of glutamate and its receptors in autism and the use of glutamate receptor antagonists in treatment

@article{Rojas2014TheRO,
  title={The role of glutamate and its receptors in autism and the use of glutamate receptor antagonists in treatment},
  author={Donald C. Rojas},
  journal={Journal of Neural Transmission},
  year={2014},
  volume={121},
  pages={891-905}
}
Glutamate is the major excitatory neurotransmitter in the brain and may be a key neurotransmitter involved in autism. Literature pertaining to glutamate and autism or related disorders (e.g., Fragile X syndrome) is reviewed in this article. Interest in glutamatergic dysfunction in autism is high due to increasing convergent evidence implicating the system in the disorder from peripheral biomarkers, neuroimaging, protein expression, genetics and animal models. Currently, there are no… CONTINUE READING
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