The role of gicerin, a novel cell adhesion molecule, in development, regeneration and neoplasia.

@article{Tsukamoto2001TheRO,
  title={The role of gicerin, a novel cell adhesion molecule, in development, regeneration and neoplasia.},
  author={Yasuhiro Tsukamoto and Eiichi Taira and Naomasa Miki and Fumihiko Sasaki},
  journal={Histology and histopathology},
  year={2001},
  volume={16 2},
  pages={563-71}
}
Neurite outgrowth factor (NOF) is an extracellular matrix (ECM) protein in the laminin family and its ligand, gicerin, is a novel cell adhesion molecule in the immunoglobulin superfamily. Gicerin has a homophilic adhesive activity as well as a heterotypic manner to NOF. In the nervous systems, gicerin is expressed during developmental stage when neurons migrate or extend neurites to form a neural network. Gicerin promotes neurite extension and migration of embryonic neurons in vitro by its… CONTINUE READING

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