The role of fructose transporters in diseases linked to excessive fructose intake.

  title={The role of fructose transporters in diseases linked to excessive fructose intake.},
  author={V{\'e}ronique Douard and Ronaldo P. Ferraris},
  journal={The Journal of physiology},
  volume={591 2},
Fructose intake has increased dramatically since humans were hunter-gatherers, probably outpacing the capacity of human evolution to make physiologically healthy adaptations. Epidemiological data indicate that this increasing trend continued until recently. Excessive intakes that chronically increase portal and peripheral blood fructose concentrations to >1 and 0.1 mm, respectively, are now associated with numerous diseases and syndromes. The role of the fructose transporters GLUT5 and GLUT2 in… CONTINUE READING


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