The role of follicle-stimulating hormone in controlling Sertoli cell proliferation in testes of fetal rats.

@article{Orth1984TheRO,
  title={The role of follicle-stimulating hormone in controlling Sertoli cell proliferation in testes of fetal rats.},
  author={Joanne M Orth},
  journal={Endocrinology},
  year={1984},
  volume={115 4},
  pages={1248-55}
}
Proliferation of Sertoli cells in the rat testis occurs only during the perinatal period and is maximal during fetal life. This interval is thus of critical importance in establishing the complement of Sertoli cells that populates the adult testis. FSH has been implicated in this process, but direct evidence in support of its involvement is lacking. In the present study, we have used in vivo and in vitro approaches to determine whether FSH produced by the fetal pituitary has a role in… CONTINUE READING

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