The role of extracellular matrix in glioma invasion: a cellular Potts model approach.

@article{Rubenstein2008TheRO,
  title={The role of extracellular matrix in glioma invasion: a cellular Potts model approach.},
  author={Brenda Rubenstein and Laura J Kaufman},
  journal={Biophysical journal},
  year={2008},
  volume={95 12},
  pages={5661-80}
}
In this work, a cellular Potts model based on the differential adhesion hypothesis is employed to analyze the relative importance of select cell-cell and cell-extracellular matrix (ECM) contacts in glioma invasion. To perform these simulations, three types of cells and two ECM components are included. The inclusion of explicit ECM with an inhomogeneous fibrous component and a homogeneously dispersed afibrous component allows exploration of the importance of relative energies of cell-cell and… CONTINUE READING
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