The role of extracellular matrix, integrins, and cytoskeleton in mechanotransduction of centrifugal loading

@article{Li2007TheRO,
  title={The role of extracellular matrix, integrins, and cytoskeleton in mechanotransduction of centrifugal loading},
  author={Juan Jenny Li and Zhihe Zhao and Jun Wang and Guoping Chen and Jingyuan Yang and Songjiao Luo},
  journal={Molecular and Cellular Biochemistry},
  year={2007},
  volume={309},
  pages={41-48}
}
The study was aimed to investigate the role of the “extracellular matrix (ECM)-integrins-cytoskeleton” signal pathway in mechanotransduction of centrifugal loading. MG-63 osteoblasts were exposed to centrifugal loading at 209×g for 10 min. Uncentrifuged cells and centrifuged cells that have been trypsinized and suspended in liquors were designed as control. The changes in F-actin and α-actin cytoskeleton, gene transcription of ECM components, and integrins expression were analyzed by LSCM, Real… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 37 references

a close relationship studied using elastic micropatterned substrates

  • NQ Balaban, US Schwartz, Riveline D et al Force, focal adhesion assembly
  • Nat Cell Biol 3:466–472 48 Mol Cell Biochem
  • 2008

A new four-point bending system to supply cultured adhensive cells in vitro with cyclic uniaxial strain

  • J Li, ZH Zhao, GP Chen
  • Key Eng Mater
  • 2007

Similar Papers

Loading similar papers…