The role of excitatory amino acids in airway reflex responses in anesthetized dogs.

@article{Haxhiu1997TheRO,
  title={The role of excitatory amino acids in airway reflex responses in anesthetized dogs.},
  author={Musa A. Haxhiu and Bernadette O. Erokwu and Ismail A. Dreshaj},
  journal={Journal of the autonomic nervous system},
  year={1997},
  volume={67 3},
  pages={
          192-9
        }
}
In these studies we examined the role of excitatory amino acids (EAAs) neurotransmission in communicating sensory inputs to the airway-related vagal preganglionic neurons, by examining the effects of either NMDA or AMPA/kainate receptor blockade on reflex and chemical responses of tracheal smooth muscle. Experiments were performed in chloralose anesthetized, paralyzed and mechanically ventilated beagle dogs (n = 18), under hyperoxic, normocapnic, and normohydric conditions. Topical application… CONTINUE READING