The role of estrogens for male bone health.

  title={The role of estrogens for male bone health.},
  author={C Ohlsson and Liesbeth Vandenput},
  journal={European journal of endocrinology},
  volume={160 6},
Sex steroids are important for the growth and maintenance of both the female and the male skeleton. However, the relative contribution of androgens versus estrogens in the regulation of the male skeleton is unclear. Experiments using mice with inactivated sex steroid receptors demonstrated that both activation of the estrogen receptor (ER)alpha and activation of the androgen receptor result in a stimulatory effect on both the cortical and trabecular bone mass in males. ERbeta is of no… CONTINUE READING