The role of estrogen and testosterone in female rats in behavioral models of relevance to schizophrenia

@article{Gogos2011TheRO,
  title={The role of estrogen and testosterone in female rats in behavioral models of relevance to schizophrenia},
  author={Andrea Gogos and Perrin T Kwek and Maarten van den Buuse},
  journal={Psychopharmacology},
  year={2011},
  volume={219},
  pages={213-224}
}
The sex steroid hormone, estrogen, may play a protective role in schizophrenia. We previously found that estrogen treatment inhibited serotonin-1A (5-HT1A) and dopamine D2 receptor-mediated disruptions of prepulse inhibition (PPI), a measure of sensorimotor gating which is deficient in schizophrenia. The present study aimed to further explore the role of sex steroid hormones in schizophrenia. Part 1 of this study examined whether estrogen could inhibit PPI disruption induced by the N-methyl-d… CONTINUE READING
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Effects of estrogen on the basal ganglia

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Highly Influential
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