The role of erythropoietin and erythropoietin receptor in malignant laryngeal tumors.

@article{Vukeli2013TheRO,
  title={The role of erythropoietin and erythropoietin receptor in malignant laryngeal tumors.},
  author={Jelena Vukeli{\'c} and Renata Dobrila-Dintinjana and Nives Jonjic and Andrea Dekani{\'c} and Vjekoslav Iliji{\'c}},
  journal={Medical hypotheses},
  year={2013},
  volume={81 6},
  pages={
          1155-8
        }
}
Erythropoietin (Epo) is a glycoprotein hormone responsible for erythropoiesis. Its effect is realized by binding erythropoietin receptor (EpoR) expressed on erythroid progenitor cells. Hypoxia is the main stimulus for the secretion of erythropoietin. Anemia is an independent negative prognostic factor for survival in patients with malignant diseases. Synthetic forms of erythropoietin are used in clinical oncology practice to increase the level of hemoglobin. As well as endogenous they can bind… CONTINUE READING

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