The role of epinephrine in the circulatory effects of coffee.

  title={The role of epinephrine in the circulatory effects of coffee.},
  author={P. G. F. M. Smits and Guido Pieters and T H Thien},
  journal={Clinical pharmacology and therapeutics},
  volume={40 4},
The circulatory response to coffee was studied in 10 normotensive, 10 bilaterally adrenalectomized, and 10 hypertensive subjects. In the normotensive group, drinking coffee exerted a rise in blood pressure (+5.1/+11.5 mm Hg), a fall in heart rate (-6.0 bpm), a rise in plasma epinephrine (+257.2%), and no change in plasma norepinephrine. The response to coffee in the hypertensive group was similar or even enhanced. In the patients who had undergone adrenalectomy, the coffee-induced rise of… CONTINUE READING
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